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ammawlaammawla/encode-toolkit/skills/regulatory-elements/SKILL.md

regulatory-elements

Skill20 starsChanged 8 months agoAGPL-3.0View on GitHub

Discover and characterize regulatory elements (enhancers, promoters, silencers, insulators, super-enhancers) using ENCODE data and the cCRE catalog. Use when the user wants to find candidate regulatory elements, identify active enhancers in a tissue, map promoter states, classify chromatin states with ChromHMM, identify super-enhancers with ROSE, understand the functional validation hierarchy (CRISPR > MPRA > reporter), or characterize non-coding genomic regions. Covers the full workflow from ENCODE cCRE lookup through chromatin state segmentation to functional validation and enhancer-gene linkage. Use this skill for ANY regulatory element discovery, classification, or characterization task.

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9 rules. About 0 are common, 9 are distinctive, and 0 are very specific to this project.

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Licensed with conditions — read it at the source. We count its rules but don't quote them. Read them on GitHub.

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