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ammawlaammawla/encode-toolkit/skills/integrative-analysis/SKILL.md

integrative-analysis

Skill20 starsChanged 8 months agoAGPL-3.0View on GitHub

Plan and execute integrative analysis combining multiple ENCODE experiments for cross-dataset or multi-omic workflows. Use when the user wants to combine experiments, perform cross-dataset comparison, multi-omic integration, peak overlap analysis, differential binding, signal correlation, chromatin state segmentation, enhancer-gene linkage, or any analysis that requires merging or comparing data from two or more ENCODE experiments. Covers same-assay cross-sample, multi-omic same-sample, cross-organism, and perturbation integration designs. Guides compatibility checks, batch effect detection, normalization, integration strategy selection, and provenance documentation.

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17 rules. About 0 are common, 15 are distinctive, and 2 are very specific to this project.

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