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PharMolixPharMolix/OpenBioMed/skills/biomedical-literature-search/SKILL.md

biomedical-literature-search

Skill1.1k starsChanged 8 months agoMITView on GitHub

Search biomedical literature from PubMed and bioRxiv for research papers. Use this skill when: (1) Finding research papers on a specific topic or disease, (2) Retrieving recent preprints from bioRxiv, (3) Getting paper titles, abstracts, and metadata, (4) Literature review for drug discovery or biomedical research.

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  • Common
  • Distinctive
  • Very specific
  1. Distinctive:

    Search PubMed and bioRxiv for biomedical research papers with titles and abstracts.

    line 17

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Files
SKILL.md

Biomedical Literature Search

Search PubMed and bioRxiv for biomedical research papers with titles and abstracts.

When to Use

  • Find research papers on a specific biomedical topic
  • Retrieve recent preprints from bioRxiv
  • Get paper titles, abstracts, authors, and links
  • Literature review for drug discovery or biomedical research

Workflow

PubMed Search (Keyword-based)

import requests
import xml.etree.ElementTree as ET

# Step 1: Search for PMIDs
search_url = "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi"
params = {"db": "pubmed", "term": "PD-1 inhibitor cancer", "retmax": 10, "retmode": "json"}
response = requests.get(search_url, params=params)
pmids = response.json()["esearchresult"]["idlist"]

# Step 2: Fetch paper details
fetch_url = "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi"
response = requests.get(fetch_url, params={"db": "pubmed", "id": ",".join(pmids), "rettype": "abstract", "retmode": "xml"})

bioRxiv Fetch (Date-range based)

import requests

# Fetch papers by date range
url = "https://api.biorxiv.org/details/biorxiv/2026-02-01/2026-03-01"
response = requests.get(url)
papers = response.json()["collection"]

for paper in papers[:5]:
    print(f"Title: {paper['title']}")
    print(f"Abstract: {paper['abstract'][:200]}...")

Expected Outputs

PubMed Results

Returns list of papers with:

FieldDescription
titlePaper title
authorsAuthor list
abstractFull abstract
doiDOI identifier
pmidPubMed ID
datePublication date
linkPubMed URL

bioRxiv Results

Returns list of papers with:

FieldDescription
titlePaper title
authorsAuthor list
abstractFull abstract
doiDOI identifier
datePublication date
categorySubject category
linkbioRxiv URL

Category Filters for bioRxiv

CategoryDescription
cancer_biologyCancer research
immunologyImmune system studies
cell_biologyCellular processes
bioinformaticsComputational biology
neuroscienceNervous system research
microbiologyMicrobial studies
genomicsGenome analysis

Error Handling

ErrorSolution
No PubMed resultsBroaden search terms, check spelling
bioRxiv timeoutReduce date range, retry
Empty abstractPaper may not have abstract available
Rate limitingAdd delay between requests (NCBI: 3 req/sec)

API References

Notes

  • PubMed: Keyword search via NCBI E-utilities API
  • bioRxiv: Date-range or category-based fetch via bioRxiv API
  • bioRxiv does not support direct keyword search
  • For comprehensive search, use both sources together

See examples/basic_example.py for complete runnable examples.

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