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BioconductorBioconductor/ai-agent-skills/skills/bioc-howto/SKILL.md

bioc-howto

Skill10 starsChanged 3 months agoMITView on GitHub

A consolidated index of Bioconductor how-to skills covering genomics, sequencing, and omics data analysis tasks

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SKILL.md

Bioconductor How-To Skills

This skill indexes a collection of focused, practical how-tos for common Bioconductor tasks. Each entry links to a dedicated file with full step-by-step instructions, required packages, example code, and further reading.

The individual how-to files are located in skills/bioc-howto/how-tos/.

Index of How-Tos

SkillDescription
compute-read-coverageCompute per-base read coverage from a BAM file using Bioconductor's GenomicAlignments package
compute-sequence-composition-for-genomic-regionsCompute GC content and CpG observed/expected ratio for genomic regions using Bioconductor
extract-promoter-sequencesExtract promoter DNA sequences for any organism's genes using Bioconductor
get-exon-intron-sequence-for-geneRetrieve exon and intron DNA sequences for a specific gene using Bioconductor
load-gene-from-gff-gtfImport a gene model from a GFF or GTF file as a TxDb object using Bioconductor
read-big-bam-file-in-chunksIterate through a large BAM file in memory-efficient chunks using Bioconductor
read-gene-sets-from-gmt-filesRead gene sets from GMT files (e.g. MSigDB) into Bioconductor GeneSetCollection objects
read-mass-spectrometry-dataLoad raw mass spectrometry data from mzML files into a Bioconductor Spectra object
read-paired-end-reads-from-bam-fileLoad paired-end reads from a BAM file as GAlignmentPairs or GAlignmentsList using Bioconductor
read-single-end-reads-from-bam-fileLoad single-end reads from a BAM file into a GAlignments object using Bioconductor
retrieve-gene-model-from-annotationhubDownload a gene model from AnnotationHub as a GRanges or GRangesList object using Bioconductor
use-tidy-principles-for-granges-manipulationManipulate GRanges objects using dplyr-style tidy verbs via the tidyomics/plyranges Bioconductor ecosystem
use-tidy-principles-for-rna-seq-analysisManipulate SummarizedExperiment and SingleCellExperiment RNA-seq objects using tidy dplyr-style verbs via tidyomics

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