Find the best CLAUDE.md, AGENTS.md and Claude skills

Google DeepMindSkill

foldseek-structural-search

google-deepmind/science-skills/skills/foldseek_structural_search/SKILL.md

Performs 3D structural searches of proteins against various databases (PDB, AlphaFold, CATH, MGnify, etc.) using the Foldseek API. Use ONLY when the user provides a physical 3D coordinate file (.cif, .mmcif, or .pdb) and wants to find structurally similar proteins. Do NOT use if the user only provides a protein sequence, gene name, or UniProt ID.

Google DeepMindSkill

gnomad-database

google-deepmind/science-skills/skills/gnomad_database/SKILL.md

Query the Genome Aggregation Database (gnomAD). Use when determining the rarity or allele frequency of specific genetic variants, retrieving gene constraint metrics (pLI, LOEUF) to assess loss-of-function intolerance, finding variants in a genomic region or gene, or querying structural variants. Don't use for analyzing individual patient genomes, tracking somatic mutations in cancer (use COSMIC), or requesting raw sequencing reads (use ENA).

Google DeepMindSkill

gtex-database

google-deepmind/science-skills/skills/gtex_database/SKILL.md

Use when you want to retrieve quantitative RNA expression data and variant eQTL information from the GTEx (Genotype-Tissue Expression) Project across 54 non-diseased tissue sites.

Google DeepMindSkill

human-protein-atlas-database

google-deepmind/science-skills/skills/human_protein_atlas_database/SKILL.md

Use when you want to retrieve semi-quantitative protein expression and spatial localisation data from the Human Protein Atlas (HPA).

Google DeepMindSkill

interpro-database

google-deepmind/science-skills/skills/interpro_database/SKILL.md

Identify domains, families, and sites in proteins; find all proteins in a family or sharing a domain; explore species distribution for a domain; annotate genomes with protein families and GO terms. InterPro combines 14 databases (e.g., Pfam, CDD) into one searchable resource. InterPro-N significantly expands annotation and sequence coverage with deep learning. Includes domain architecture (IDA) search.

Google DeepMindSkill

jaspar-database

google-deepmind/science-skills/skills/jaspar_database/SKILL.md

Query the JASPAR database for Transcription Factor (TF) binding profiles. Use when retrieving Position Frequency Matrices (PFMs) or Position Weight Matrices (PWMs) for specific TFs, resolving gene symbols to JASPAR Matrix IDs, or getting TF metadata. Supports multiple output formats (MEME, TRANSFAC, PFM, JASPAR, YAML).

Google DeepMindSkill

literature-search-arxiv

google-deepmind/science-skills/skills/literature_search_arxiv/SKILL.md

Search for scientific papers, preprints, and publications on arXiv. Extract metadata, abstracts, and download full-text PDFs or HTML versions of papers. Use when the user asks to find research papers, literature, or specific arXiv IDs.

Google DeepMindSkill

literature-search-biorxiv

google-deepmind/science-skills/skills/literature_search_biorxiv/SKILL.md

Browse and filter life sciences, biology, and medical preprints from bioRxiv and medRxiv. Supports fetching paper metadata by DOI, and browsing by date range with category and keyword filters. Keyword filtering is local, so date ranges MUST be narrow (1-4 weeks) with a category to prevent timeouts.

Google DeepMindSkill

literature-search-europepmc

google-deepmind/science-skills/skills/literature_search_europepmc/SKILL.md

Search Europe PMC for scientific literature and download open-access full texts and PDFs. Retrieve full-text XML/plain text by PMCID, get citation lists and bibliography.

Google DeepMindReads credentialsSkill

literature-search-openalex

google-deepmind/science-skills/skills/literature_search_openalex/SKILL.md

Query the OpenAlex scholarly database for research papers, authors, institutions, topics, sources, publishers, funders, geo-locations, and keywords. Use when searching academic papers, resolving DOIs, downloading open-access PDFs, finding an author's publications, aggregating bibliometric data (citation counts, h-index, impact factor), exploring the research taxonomies, or performing DOI lookups.

Google DeepMindReads credentialsSkill

ncbi-sequence-fetch

google-deepmind/science-skills/skills/ncbi_sequence_fetch/SKILL.md

Retrieve protein and nucleotide sequences from NCBI databases using E-utilities. Supports direct accession lookup, CDS translation, gene+organism search, locus lookup, PubMed-linked sequences, patent protein extraction, and organism+length fallback search. Use when you need to fetch biological sequences by accession, gene name, locus tag, PubMed ID, or patent number.

Google DeepMindReads credentialsSkill

openfda-database

google-deepmind/science-skills/skills/openfda_database/SKILL.md

Query, search, and download data from the openFDA API for drugs, devices, foods, tobacco, cosmetics, animal and veterinary products, substances, and transparency data. Use for FDA adverse events, recalls, labeling, approvals, shortages, 510(k) clearances, NDC lookups, and any FDA safety or regulatory data query across all 28 API endpoints.

Google DeepMindSkill

opentargets-database

google-deepmind/science-skills/skills/opentargets_database/SKILL.md

Query Open Targets Platform for target-disease associations, drug target discovery, tractability/safety data, genetics/omics evidence, known drugs, for therapeutic target identification.

Google DeepMindSkill

pdb-database

google-deepmind/science-skills/skills/pdb_database/SKILL.md

Use when you want to search for or download experimentally-determined 3D structures for biomolecules (proteins, nucleic acids, bound ligands). Supports searching by sequence similarity, structure similarity, chemical and other attributes. Also use to get metadata about biomolecular structure experiments.

Google DeepMindSkill

predictingthepast

google-deepmind/science-skills/skills/predictingthepast/SKILL.md

Ancient text restoration, attribution, dating, contextualization, and embedding via Aeneas (Latin) / Ithaca (Ancient Greek). Use when asked to "restore", "attribute", "date", "contextualize", "find parallels", "where was it written", "when was it written", "embed", or "analyze" an ancient text, inscription, or epigraphic document, or when the user mentions "Aeneas", or "Ithaca".

Google DeepMindReads credentialsSkill

protein-sequence-msa

google-deepmind/science-skills/skills/protein_sequence_msa/SKILL.md

Performs multiple sequence alignment of proteins with EBI Clustal Omega. Use when you need to align multiple sequences to assess similarity, domain conservation, or key residue conservation. Supports up to 4000 sequences and a maximum file size of 4 MB. Do not use to search for homologous proteins in a database (use MMseqs2, BLAST), align non-protein sequences (DNA, RNA), perform structural alignment (use Foldseek, PyMOL), or if you only have a single sequence.

Google DeepMindReads credentialsSkill

protein-sequence-similarity-search

google-deepmind/science-skills/skills/protein_sequence_similarity_search/SKILL.md

Searches for homologous protein sequences using MMseqs2 (fast, default) or BLAST (comprehensive, fallback). Trigger this whenever the user provides a protein sequence or FASTA file and asks to find homologues, sequence matches, or wants to infer protein function based on sequence similarity, but not when the user wants to infer protein function based on structural similarity.

Google DeepMindSkill

pubchem-database

google-deepmind/science-skills/skills/pubchem_database/SKILL.md

Query PubChem, search by name/CID/SMILES, retrieve properties, similarity/substructure searches, bioactivity, for cheminformatics. Use when a user asks about a specific chemical, drug, or molecule.

Google DeepMindReads credentialsSkill

pubmed-database

google-deepmind/science-skills/skills/pubmed_database/SKILL.md

Search PubMed for scientific literature, including published clinical trials. Fetch abstracts and full text. Link published research to biological databases (gene, protein, nucleotide, PubChem) to discover associations between papers and specific compounds or genes. Verify medical spelling, match raw citations, and cache result sets for bulk processing. Interfaces NCBI E-utilities and PMC BioC APIs.

Often used withuspto-database·ena-database·gwas-database

Google DeepMindSkill

pymol

google-deepmind/science-skills/skills/pymol/SKILL.md

Visualize, analyze, and render protein and molecular structures using PyMOL. Use when the user wants to create images of protein structures, perform structural alignments or superposition, measure distances or contacts, highlight binding sites or active site residues, color by B-factor/pLDDT, or analyze protein-ligand interactions. Do not use for docking, molecular dynamics, or sequence-only analysis.