Skills real projects publish on GitHub, most starred first. Each one says what it will make an agent do before you copy it.
OpenAISkillopenai/plugins/plugins/hyperframes/skills/gsap/SKILL.md
GSAP animation reference for HyperFrames. Covers gsap.to(), from(), fromTo(), easing, stagger, defaults, timelines (gsap.timeline(), position parameter, labels, nesting, playback), and performance (transforms, will-change, quickTo). Use when writing GSAP animations in HyperFrames compositions.
OpenAISkillopenai/plugins/plugins/hyperframes/skills/hyperframes-cli/SKILL.md
HyperFrames CLI tool — hyperframes init, lint, inspect, preview, render, transcribe, tts, doctor, browser, info, upgrade, compositions, docs, benchmark. Use when scaffolding a project, linting, validating, inspecting visual layout in compositions, previewing in the studio, rendering to video, transcribing audio, generating TTS, or troubleshooting the HyperFrames environment.
OpenAISkillopenai/plugins/plugins/hyperframes/skills/hyperframes-registry/SKILL.md
Install and wire registry blocks and components into HyperFrames compositions. Use when running hyperframes add, installing a block or component, wiring an installed item into index.html, or working with hyperframes.json. Covers the add command, install locations, block sub-composition wiring, component snippet merging, and registry discovery.
OpenAISkillopenai/plugins/plugins/hyperframes/skills/hyperframes/SKILL.md
Create video compositions, animations, title cards, overlays, captions, voiceovers, audio-reactive visuals, and scene transitions in HyperFrames HTML. Use when asked to build any HTML-based video content, add captions or subtitles synced to audio, generate text-to-speech narration, create audio-reactive animation (beat sync, glow, pulse driven by music), add animated text highlighting (marker sweeps, hand-drawn circles, burst lines, scribble, sketchout), or add transitions between scenes (crossfades, wipes, reveals, shader transitions). Covers composition authoring, timing, media, and the full video production workflow. For CLI commands (init, lint, preview, render, transcribe, tts) see the hyperframes-cli skill.
OpenAISkillopenai/plugins/plugins/hyperframes/skills/website-to-hyperframes/SKILL.md
Capture a website and create a HyperFrames video from it. Use when: (1) a user provides a URL and wants a video, (2) someone says "capture this site", "turn this into a video", "make a promo from my site", (3) the user wants a social ad, product tour, or any video based on an existing website, (4) the user shares a link and asks for any kind of video content. Even if the user just pastes a URL — this is the skill to use.
OpenAISkillopenai/plugins/plugins/life-science-research/skills/alphafold-skill/SKILL.md
Submit compact AlphaFold Protein Structure Database API requests for prediction, UniProt summary, sequence summary, and annotation lookups. Use when a user wants AlphaFold metadata or concise structure summaries
OpenAISkillopenai/plugins/plugins/life-science-research/skills/bgee-skill/SKILL.md
Submit compact Bgee SPARQL requests for healthy wild-type expression metadata and ontology-aware lookup patterns. Use when a user wants concise Bgee summaries; save raw results only on request.
OpenAISkillopenai/plugins/plugins/life-science-research/skills/bindingdb-skill/SKILL.md
Submit compact BindingDB REST API requests for ligand-target binding lookups by PDB, UniProt, or similarity search. Use when a user wants concise BindingDB summaries; save raw payloads only on request.
OpenAISkillopenai/plugins/plugins/life-science-research/skills/biobankjapan-phewas-skill/SKILL.md
Fetch compact BioBank Japan PheWAS summaries for single variants by accepting rsID, GRCh38, or GRCh37 input and resolving to the required GRCh37 query. Use when a user wants concise BBJ association results for one variant
OpenAISkillopenai/plugins/plugins/life-science-research/skills/biorxiv-skill/SKILL.md
Submit compact bioRxiv and medRxiv API requests for details, publication-linkage, and DOI lookups. Use when a user wants concise preprint metadata summaries
OpenAISkillopenai/plugins/plugins/life-science-research/skills/biostudies-arrayexpress-skill/SKILL.md
Submit compact BioStudies and ArrayExpress API requests for free-text search and accession-based study retrieval. Use when a user wants concise BioStudies summaries
OpenAISkillopenai/plugins/plugins/life-science-research/skills/cbioportal-skill/SKILL.md
Submit compact cBioPortal API requests for studies, molecular profiles, mutations, clinical data, and samples. Use when a user wants concise cBioPortal summaries
OpenAISkillopenai/plugins/plugins/life-science-research/skills/cellxgene-skill/SKILL.md
Submit compact CELLxGENE Discover API requests for public collection and dataset metadata. Use when a user wants concise single-cell collection summaries
OpenAISkillopenai/plugins/plugins/life-science-research/skills/chebi-skill/SKILL.md
Submit compact ChEBI 2.0 API requests for chemical search, compound lookup, ontology traversal, and structure metadata. Use when a user wants concise ChEBI summaries
OpenAISkillopenai/plugins/plugins/life-science-research/skills/chembl-skill/SKILL.md
Submit compact ChEMBL API requests for activity, molecule, target, mechanism, and text-search endpoints. Use when a user wants concise ChEMBL summaries
OpenAISkillopenai/plugins/plugins/life-science-research/skills/civic-skill/SKILL.md
Submit compact CIViC GraphQL requests for cancer variant interpretation schema inspection and targeted evidence retrieval. Use when a user wants concise CIViC summaries
OpenAISkillopenai/plugins/plugins/life-science-research/skills/clinicaltrials-skill/SKILL.md
Submit compact ClinicalTrials.gov API v2 requests for study search, metadata, enums, search areas, and field statistics. Use when a user wants concise ClinicalTrials.gov summaries
OpenAISkillopenai/plugins/plugins/life-science-research/skills/clinvar-variation-skill/SKILL.md
Submit compact ClinVar Clinical Tables and NCBI Variation requests for search, VCV, RCV, SCV, and RefSNP lookups. Use when a user wants variant-level summaries or identifier mapping
OpenAISkillopenai/plugins/plugins/life-science-research/skills/efo-ontology-skill/SKILL.md
Submit compact EFO OLS4 requests for search, term lookup, children, and descendants. Use when a user wants concise EFO resolution or ontology-expansion summaries
OpenAISkillopenai/plugins/plugins/life-science-research/skills/encode-skill/SKILL.md
Submit compact ENCODE REST API requests for object lookups, portal-style search, and metadata retrieval. Use when a user wants concise ENCODE summaries
A folder with a SKILL.md file: a name, a description of when to use it, and instructions. Claude loads a skill only when the task matches its description.
Copy the folder into your project's .claude/skills/ directory, or into your own skills folder to use it everywhere.
We read each file for commands that read secrets, delete things or pipe downloads into a shell, and say so before you copy it. No warning is not a promise that a file is safe.
Open a skill to see its discussion. Reports from people and their agents are coming.
